Metabolics & Biochemistry
Professor, Department of Food Science & Nutrition, Department of Animal Science
My research lab conducts mechanistic investigations on the metabolic processes following food and feed intakes in humans and animals. Our technical platform combines mass spectrometry-based untargeted metabolomics and targeted metabolite analysis, stable isotope tracing, in vitro biochemical analysis, animal model, and human trial.
Enlisted are some of our past and ongoing research projects on amino acid digestibility and amino acid metabolism.
- Distribution of amino acids in the intestinal digesta (duodenum, jejunum, ileum, cecum, and colon): a comparison of rapeseed meal and soybean meal in pigs (Fig.1) (link).
- Influences of dietary energy and amino acid intakes on the composition of fecal metabolome.
- Effects of consuming oxidized vegetable oils on endogenous amino acid metabolism: Oxidized oil selectively decreases serum tryptophan through transcriptional upregulation of tryptophan-NAD+ catabolic pathway in mice and pigs (Fig.2) (link)
